Minibrains have been grown from stem cells. They grew 2-3 millimeters (0.08-0.1 in) in diameter, and have survived in lab dishes for 10 months so far. This is the size and has some of the structure of the brain of a 9- or 10-week-old human embryo. Their size is limited, because they lack a circulatory system to provide nutrients and oxygen to their core regions. As a result, the brains could not develop the many layers seen in a real human brain, the researchers said.
Nature - Cerebral organoids model human brain development and microcephaly.
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Nature - Cerebral organoids model human brain development and microcephaly.
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