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70 more intelligence related genes found

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At a European Society of human genetics talk a scientist reported 70 genome wide hits for genes associated with human intelligence.

An older paper reported 18 genome wide hits for genes associated with human intelligence.

Genome-wide association study of 200,000 individuals identified 18 genome-wide significant loci and provides biological insight into human cognitive function.

Educational attainment, measured as years of schooling, is commonly used as a proxy for cognitive function. A recent genome wide association study (GWAS) of educational attainment conducted in a discovery sample of 100,000 individuals identified and replicated three genome-wide significant loci. Here, we report preliminary results based on conducted in 200,000 individuals. We replicate the previous three loci and report 15 novel, genome-wide significant loci for educational attainment. A polygenic score composed of 18 single nucleotide polymorphisms, one from each locus, explains ~0.4% of the variance educational attainment.

Steve Hsu has estimated a few thousand to ten thousand genetic variations explain the genetic basis of human intelligence. A study of about a million people should enable the genetic differences of intelligence to be found.

There was a review of five years of genome-wide association studies in 2011.



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